hepatitis d virus infection among hepatitis b surface antigen carriers and in “isolated anti-hbc” antibodies profile in central tunisia
نویسندگان
چکیده
conclusions although hdv had low prevalence in our area, it is vital to plan preventive strategies for hdv spread as well as hbv prevention. it is particularly important to suspect hdv infection in active hbv carriers to manage a particularly severe dual infection. hdv infection should be suspected even in negative hbsag patients having “isolated anti-hbc” profile. results prevalence of hdv was 8.1% in hbsag carriers group, but it was significantly higher in active than inactive hepatitis (30.2% and 4.5%, respectively, or = 9, 95% ci: [4.48-18.58]). there was no significant association between studied risk factors and hdv infection. in the “isolated anti-hbc” profile group, prevalence of hdv was 4.6% and hbv-dna had negative result in all patients with positive results for hdv. background hepatitis d virus (hdv) causes accelerated liver diseases in patients with hepatitis b virus (hbv) infection. there is lack of data about its prevalence, related risk factors and interaction with hbv carriers in our country. objectives the aim of this study was to estimate the prevalence of hepatitis delta and associated risk factors among hepatitis b surface antigen (hbsag) and “isolated anti-hbc” profile carriers in central tunisia. patients and methods in this cross-sectional study, 540 patients with positive hbsag and 109 “isolated anti-hbc” profile receiving care in a teaching hospital were tested for the presence of hdv serum-markers using commercially available enzyme immunoassay kit. hbv-dna was detected by nested pcr in “isolated anti-hbc” profile group.
منابع مشابه
Hepatitis D Virus Infection Among Hepatitis B Surface Antigen Carriers and in “Isolated anti-HBc” Antibodies Profile in Central Tunisia
BACKGROUND Hepatitis D Virus (HDV) causes accelerated liver diseases in patients with Hepatitis B Virus (HBV) infection. There is lack of data about its prevalence, related risk factors and interaction with HBV carriers in our country. OBJECTIVES The aim of this study was to estimate the prevalence of hepatitis delta and associated risk factors among Hepatitis B surface antigen (HBsAg) and "i...
متن کاملHEPATITIS B VIRUS INFECTION IN AN ANTI-HBC NEGATIVE PATIENT: A CASE REPORT
ABSTRACT One of the best reliable markers of hepatitis B virus infection is antibodies to the core antigen (Anti-HBc). A first-time blood donor with HBsAg positivity was identified as an HBV carrier that was anti-HBc negative. The patient was followed for 24 months in order to investigate the evolution of his HBV serological profiles and HBVDNA (PCR). In the follow-up for 24 months, HBsAg, HBe...
متن کاملThe Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran
Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...
متن کاملIndication of Anti-HBc Antibody Screening and HBV-DNA Detection in Diagnosing Latent Hepatitis B Virus Infection
Background: In spite of available, and sensitive screening assay for detection of hepatitis B virus surface antigen (HBsAg), occasional cases of post-transfusion hepatitis B virus infection are still observed. The aim of the present study was to assess the prevalence of positive anti hepatitis B core (anti-HBc) and presence of HBV-DNA in serum sample of healthy blood donors negative for both HB...
متن کاملAnti-HBc and HBV-DNA detection in blood donors negative for hepatitis B virus surface antigen
Occult HBV infection is defined as the presence of hepatitis B virus (HBV) DNA in blood or liver tissues in patients negative for Hepatitis B surface Antigen (HBsAg). Those patients may or may not be positive for HBV antibodies. The objective of this study is to determine the presence or absence of HBV DNA in the serum samples from HBsAg negative blood donors. In addition we aimed to assess the...
متن کاملIntra-familial Transmission of Hepatitis B Virus Infection in Arak, Central Iran
Background: The household transmission of hepatitis B virus (HBV) is a major health problem. High incidence of HBV infection is observed within the household contacts of HBV carriers. We aimed to evaluate serological markers of hepatitis B infection among family members of HBV carriers in Arak, central Iran. Methods<stron...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
hepatitis monthlyجلد ۱۶، شماره ۱، صفحات ۰-۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023